{'Entry': 'O51625', 'Protein names': 'tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)', 'Function': 'Catalyzes the 2-thiolat

{'Entry': 'O51625', 'Protein names': 'tRNA-specific 2-thiouridylase MnmA (EC 2.8.1.13)', 'Function': 'Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. {ECO:0000255|HAMAP-Rule:MF_00144}.', 'Subunit structure': '', 'Tissue specificity': '', 'Temperature dependence': '', 'pH dependence': '', 'Catalytic activity': 'CATALYTIC ACTIVITY: Reaction=AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]; Xref=Rhea:RHEA:47032, Rhea:RHEA-COMP:10131, Rhea:RHEA-COMP:11726, Rhea:RHEA-COMP:11727, Rhea:RHEA-COMP:11728, ChEBI:CHEBI:13193, ChEBI:CHEBI:15378, ChEBI:CHEBI:17499, ChEBI:CHEBI:29950, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:61963, ChEBI:CHEBI:65315, ChEBI:CHEBI:87170, ChEBI:CHEBI:456215; EC=2.8.1.13; Evidence={ECO:0000255|HAMAP-Rule:MF_00144};', 'Organism': 'Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)', 'Involvement in disease': '', 'Induction': ''}